Aldomet Methyldopa 500 mg 60 Tabs

500 mg
In stock
$53.86
Strength: 500 mg
Package Size: 60 Tabs
Substance: Methyldope
Manufacturer: Aspen Labs. S.A C.V
Spanish Name: Aldomet
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Aldomet is an antihypertensive medicine used to lower blood pressure. The active substance Methyldop 500 mg, which is part of Aldomet, acts on the central nervous system, relaxing blood vessels and reducing peripheral resistance, which helps to lower blood pressure. The drug is especially prescribed for arterial hypertension, including its chronic forms and hypertension in pregnancy.
 

Classification Mechanism of Action Advantages

Aldomet drug class

The drug Aldomet MOA, is classified as a central alpha-adrenomimetic because it affects the alpha-2-adrenoreceptors of the brain and the vascular system. The action of these drugs is aimed at reducing the activity of the sympathetic nervous system, which leads to a decrease in peripheral vascular resistance and, consequently, a decrease in blood pressure.

Key processes

After ingestion of Aldomet, its active ingredient, methyldop, penetrates the blood-brain barrier where it is converted into the active metabolite, alpha-methylnoradrenaline. This metabolite has a key effect on brain neurons, helping to lower blood pressure.

Aldomet affects alpha-2-adrenoreceptors, resulting in decreased sympathetic activity and reduced vascular resistance. As a result, blood pressure is lowered, but without drastic changes in heart rate or tachycardia, which reduces the risk of complications.

The drug Aldomet relaxes vascular smooth muscle and reduces peripheral arterial resistance, providing blood pressure control without affecting heart rhythm. This effect is particularly useful in chronic hypertension, including that associated with pregnancy.
 

Benefits
 

Safety of Aldomet in Pregnancy: The drug is often prescribed to pregnant women with hypertension, as it is considered one of the safest drugs for expectant mothers, with minimal risks to the fetus.

Suitable for long-term treatment: Aldomet 500, can be used on a long-term basis, as its action is aimed at a stable reduction of pressure without sharp fluctuations.

Mild and controlled vascular effects: Aldomet's classification as a central alpha-adrenomimetic ensures its mild effects on the vascular system, which reduces the likelihood of side effects such as acute vasodilation.
 

Dosage
 

The recommended dosage of Aldomet depends on the severity of the disease, the characteristics of the patient's body, and other factors. Usually, treatment is started with a lower dose, gradually increasing. For an adult patient, the initial dose may be 500 mg of Aldomet per day, divided into two doses. The maximum daily dose usually does not exceed 3 g (or 6 tablets). Tablets are recommended to be taken with meals to reduce the likelihood of gastrointestinal side effects.
 

Contraindications
 

  • Liver disease, including hepatitis and cirrhosis;
  • allergic reactions to methyldopa;
  • presence of active pheochromocytoma (adrenal tumor);
  • in cases where the patient is already receiving therapy with monoamine oxidase inhibitors (MAOIs);
  • anemia associated with iron deficiency.

Taking Aldomet tablets may also require caution in patients with kidney and cardiovascular disease.
 

Possible side effects
 

Aldomet medication is usually well tolerated, but like any medication, it can cause side effects. Some of the possible adverse reactions include the following:

  • drowsiness and fatigue;
  • dizziness and headache;
  • dry mouth;
  • decreased heart rate (bradycardia);
  • fluid retention and swelling.
     

Interactions with other drugs
 

Understanding the interactions of Aldomet with other medicines is essential to ensuring safe and effective treatment.

Interactions with antihypertensive drugs: Aldomet may interact with other antihypertensive drugs, increasing their effect. Combined use may lead to an excessive decrease in blood pressure, which may cause symptoms of hypotension such as dizziness, weakness or fainting. Therefore, when used in combination, blood pressure should be monitored and dosages adjusted if necessary.

Effect on the central nervous system: Methyldopa may increase the effects of sedatives and sleeping pills, such as benzodiazepines and opiates. This is because Aldomet by itself has an effect on the central nervous system, and its combination with other CNS-depressants may result in an increased sedative effect.

Drugs affecting the metabolism of methyldopa: Some drugs may affect the metabolism of methyldopa, which may alter its efficacy. For example, monoamine oxidase inhibitors (MAOIs) may increase the hypotensive effect of methyldopa, which makes it necessary to carefully monitor the patient's condition when using these drugs at the same time. It is important to avoid combining Aldomet with MAO inhibitors, as this may lead to sudden fluctuations in blood pressure.

Interaction with drugs for the treatment of diabetes: Aldomet may potentially affect blood glucose levels, which is important to consider in patients with diabetes mellitus. Co-administration of Aldomet with antidiabetic agents may require dose adjustment of the latter to achieve optimal blood sugar control.
 

Aldomet: Questions about the use, availability and history of the drug
 

Aldomet, whose generic name is Methyldopa, has long been used to treat arterial hypertension, especially in pregnant women. This drug is considered safe and effective, making it a popular choice among physicians to control blood pressure in expectant mothers.
 

Aldomet and pregnancy: discussion in forums
 

On specialized forums, such as Aldomet in gravidanza forum, you can find many discussions about the use of the drug during pregnancy. Many users share their experiences, including treatment results and possible side effects. Since hypertension can significantly complicate pregnancy, discussions in such communities help women make informed decisions and find support among other expectant mothers.
 

Generic name: Aldomet
 

Methyldopa is the generic name for Aldomet, and its form is often used in clinical practice. The drug belongs to the class of central alpha-adrenomimetics and works by reducing sympathetic activity, which helps lower blood pressure. Despite its effectiveness, many patients and doctors are looking for alternatives, especially since Aldomet has been temporarily taken off the market in some countries.
 

Purchasing Aldomet
 

For those interested in purchasing Aldomet, there are various options available. You can buy Aldomet at local pharmacies or go to online pharmacies. Purchasing online has its advantages, such as the ability to compare prices and the convenience of ordering from the comfort of your own home.

Many patients prefer to buy Aldomet online, as it saves time and often money. However, it is important to choose reliable and trusted online pharmacies to avoid fakes and low-quality drugs. Before buying, it is worthwhile to carefully read reviews about the store and check for licenses.
 

Reasons for Aldomet's removal from the market
 

Many users ask: Why was Aldomet discontinued? Reasons can range from side effects seen in clinical trials to issues related to manufacturing standards. Although Aldomet remains an effective treatment for hypertension, its availability may be limited due to legal and commercial factors. Patients are advised to consult their physician about possible alternatives.

Strength
500 mg
Package Size
60 Tabs
Substance
Methyldope
Manufacturer
Aspen Labs. S.A C.V
Spanish Name
Aldomet
ReviewsAldomet Methyldopa 500 mg 60 Tabs

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