Artridol Bevodinix Gel 500mg/50mg 60Grams Indomethacin / Betamethasone

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Artridol Bevodinix Gel, the trade name of a combination product combining the active ingredients indomethacin and betamethasone, is an innovative solution in the field of topical treatment of musculoskeletal disorders. Containing 500 mg of indomethacin and 50 mg of betamethasone per 60 grams of product, this gel is designed to provide effective and targeted relief of pain, inflammation and swelling in the affected area.

What is Artridol Bevodinix Gel for?

Artridol Bevodinix Gel is intended for topical application to treat a variety of conditions, including arthritis, bursitis, tendonitis, and other inflammatory conditions of the joints and surrounding tissues. Through the combination of indomethacin, a powerful non-steroidal anti-inflammatory drug (NSAID), and betamethasone, a synthetic glucocorticoid, this gel helps reduce inflammation and pain.

How long does it work?

The effect of Artridol Bevodinix Gel begins within minutes of application and can last for several hours, depending on the individual characteristics of the body and the severity of the inflammatory process. It is recommended to apply the gel to the affected areas 2–3 times a day to achieve the best effect.

Gel dosage

Artridol Bevodinix Gel, with its unique combination of active ingredients, indomethacin and betamethasone, is a powerful remedy for the treatment of inflammatory diseases of the musculoskeletal system. The dosage of this drug may vary depending on the specific disease and its severity, as well as the individual characteristics of the patient.


When treating arthritis, including rheumatoid arthritis and osteoarthritis, Artridol Bevodinix Gel is usually applied in a thin layer to the affected joint 2–3 times a day. It is important to spread the gel evenly over the entire surface of the joint, ensuring complete coverage.

Bursitis and Tendinitis

Bursitis and tendonitis are characterized by inflammation of the synovial joints and tendons, respectively. For these conditions, it is recommended to apply the gel to the area around the inflamed area, rubbing lightly until fully absorbed. Application can be done 2–4 times a day, depending on the degree of pain and inflammation.

Sports Injuries

For sports injuries such as sprains and bruises, Artridol Bevodinix Gel can help reduce inflammation and pain. Apply the gel to the affected area 3–4 times a day for symptomatic relief. Gently rubbing the gel in helps to enhance its analgesic effect.


  • The standard dosage of Artridol Bevodinix Gel is a small amount (about the size of a pea) on the affected area. It is important to rub the gel thoroughly until it is completely absorbed and to avoid contact with open wounds or damaged skin.
  • Apply the gel to clean and dry skin.
  • Avoid getting the gel on open wounds or in the eyes.
  • Wash your hands after applying the gel, unless the treatment is for your hands.
  • The duration of use should be limited to the minimum possible period.


Contraindications to the use of Artridol Bevodinix include, but are not limited to:

  • Hypersensitivity to indomethacin, betamethasone or other components of the drug
  • Active ulcerative diseases of the gastrointestinal tract
  • Diseases of an inflammatory nature in the intestinal tract, including conditions such as ulcerative colitis and Crohn's disease
  • Third trimester of pregnancy and lactation period
  • Pediatric age below 12 years of age
  • Severe liver and kidney dysfunction
  • Heart failure

Side effects

Side effects from the use of Artridol Bevodinix may occur as local and systemic reactions.

Local side effects

  • Skin irritation, redness, itching or burning at the application site
  • Allergic reactions, including contact dermatitis
  • Dryness or flaking of the skin

Systemic side effects

  • Gastroenterologic discomfort including motion sickness, emetic reactions, liquid stools, and peritoneal cramps
  • Dizziness, headache
  • Increased blood pressure and fluid retention
  • Increased risk of gastrointestinal bleeding and ulcers
  • Sleep disorders, increased fatigue

Interaction with other drugs

Artridol Bevodinix, a combination drug containing indomethacin and betamethasone, is intended for topical application and has a pronounced anti-inflammatory and analgesic effect. However, an important aspect of the use of this drug is its interaction with other drugs.

Interaction with nonsteroidal anti-inflammatory drugs (NSAIDs)

Since Artridol Bevodinix already contains an NSAID component (indomethacin), its co-administration with other NSAIDs may increase the risk of side effects, especially those related to the gastrointestinal tract, such as ulcers and bleeding.

Interaction with anticoagulants

Indomethacin, like many other NSAIDs, may interact with anticoagulants (e.g., warfarin), increasing their effects and increasing the risk of bleeding. Therefore, careful medical control is required during the concomitant use of these drugs.

Interaction with diuretics and antihypertensive drugs

Indomethacin may reduce the effectiveness of some antihypertensive drugs, including diuretics, beta-blockers and ACE inhibitors. This is due to its ability to reduce renal blood flow, which may lead to a decrease in the effectiveness of these drugs in controlling blood pressure.

Interaction with corticosteroids

Given that Artridol Bevodinix contains betamethasone, its combined use with other corticosteroids (including systemic administration) may increase the risk of systemic side effects such as Cushing's syndrome, weight gain, increased blood pressure and others.

Interaction with cytochrome P450

Indomethacin may interact with cytochrome P450 enzymes, which may alter the metabolism and blood concentrations of other drugs metabolized by these enzymes. This requires careful consideration when prescribing drugs metabolized by the same enzymes as indomethacin.

How much is in the body, and what are the routes of excretion?

As a topical agent, Artridol Bevodinix Gel acts mainly in the area of application, with minimal absorption into the systemic bloodstream. However, a certain amount of active components can be absorbed and excreted from the body, mainly through the kidneys. The time that the drug is in the body can vary, but usually the active ingredients are metabolized and excreted within a few hours after application.

Bevodinix gel plm

Bevodinix gel plm (medical professionals' literature) provides detailed information about the composition, mechanism of action, clinical use, dosage, side effects, contraindications and other important aspects related to the drug Artridol Bevodinix Gel. This information is extremely important for medical professionals when prescribing and using the drug to ensure its efficacy and safety for patients.

The price of Bevodinix gel containing indomethacin and betamethasone in Mexico varies depending on the pharmacy or online pharmacy. Generally, the cost of the medication is much lower at online pharmacies.

If you choose to purchase this medication online, it is important to make sure you are using a registered and licensed pharmacy. Our certified online pharmacy offers express delivery to various regions and provides confidential and secure transactions. Before starting any new medication, be sure to consult with a medical professional to make sure it is right for you.

Summarizing the above information

Artridol Bevodinix Gel is a powerful topical combination product designed to relieve inflammation and pain in joints and soft tissues. Its unique formula, which combines indomethacin and betamethasone makes it an effective choice for treating a variety of musculoskeletal conditions. However, as with any medication, it is important to carefully read the instructions for use, possible side effects and contraindications, and consult your doctor to ensure the best treatment results and minimize risks.

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