Lotensin is the Spanish name for a medicine whose main active ingredient is benazepril. This substance belongs to a class of medicines known as ACE inhibitors, which stands for angiotensin-converting enzyme. This enzyme plays a key role in the blood pressure regulation system in our body. Thanks to this enzyme, Lotensin helps to lower blood pressure by dilating the blood vessels. This drug also comes in a combination form called Lotensin HCT, which includes not only benazepril but also the diuretic hydrochlorothiazide. This supplement enhances the hypotensive effect by eliminating excess fluid from the body.
The mechanism of action of Benazepril Lotensin is by affecting the ACE enzyme, namely:
Benazepril blocks the action of the ACE enzyme. Normally, this enzyme converts the hormone angiotensin I into angiotensin II, which is a very powerful vasoconstrictor. Angiotensin II causes blood vessels to constrict, which is what raises blood pressure.
By blocking the creation of angiotensin II, blood vessels do not constrict, but instead dilate. The dilated vessels allow blood to flow more freely, lowering the overall pressure in the system.
Thus, Lotensin's main mechanism of action is to reduce the amount of angiotensin II in the body, which results in lower pressure in the arteries. This makes Lotensin effective in controlling hypertension.
The medication is mainly intended to stabilize blood pressure, where the pressure of blood on the walls of the arteries is too high, which can lead to various heart and vascular diseases.
Apart from this, Lotensin can be used in some other cases, such as protecting kidney function in diabetic patients who show signs of beginning kidney damage. This is because the drug helps to reduce the strain on the kidneys by reducing the pressure in their small blood vessels.
Doctors may also prescribe this drug to treat heart failure. In this condition, the heart cannot pump blood efficiently, and the use of Lotensin helps to improve this function by reducing the workload on the heart and improving blood supply to the organs.
For hypertension, the treatment should be started with a dose of 10 mg once a day. But depending on the body's reaction to the drug and the level of blood pressure, the dose can be gradually increased, but it should not exceed 40 mg per day.
In the treatment of heart failure, the initial dose may be lower to assess the body's tolerance to the drug. It is usually started with 5 mg once a day, and if the drug is well tolerated, the dose is gradually increased to the dose prescribed by the doctor.
To protect the kidneys in diabetics, the dose is also selected individually, based on the level of blood pressure and kidney function. Usually start with a low dose, gradually adjusting it according to the patient's needs.
Tablets should be taken whole, without chewing or crushing, preferably at the same time each day to maintain a uniform concentration of the drug in the blood.
Dosage may be adjusted depending on other medications being taken and the presence of conditions such as renal or hepatic impairment.
Pressure stability, results from taking Lotensin 10 mg tablets, may become apparent within a few hours of taking them, but the most noticeable reduction in blood pressure is usually seen after several weeks of regular use.
The half-life of the drug Lotensin, i.e., the time during which the concentration of the drug in the blood decreases by half, is approximately 10–11 hours, which allows maintaining a stable level of the active substance in the body when taking the drug once a day.
Diuretics: When Lotensin is used along with diuretics, the effects of the diuretics may be amplified, resulting in a greater drop in blood pressure. This may cause dizziness or even fainting, especially after standing up.
Medications to treat rheumatic diseases: Gold-containing drugs used to treat rheumatism may cause hypersensitivity reactions when used together with Lotensin.
Lithium: Lotensin may increase lithium levels in the blood, which increases the risk of lithium toxicity. If you are taking lithium, you should have your lithium levels checked regularly.
Blood sugar medications: If you are taking medications to control diabetes, Lotensin may increase their effects, potentially leading to hypoglycemia (low blood sugar).
Non-steroidal anti-inflammatory drugs: NSAIDs such as ibuprofen or naproxen may reduce the effectiveness of the medication Lotensin in controlling blood pressure. In addition, taking them together may increase the risk of kidney failure.
Potassium: Diuretics containing potassium, or potassium supplements, may cause an increase in blood potassium levels when taken at the same time as Lotensin, which is dangerous to the heart.
If you are looking for where to buy Lotensin online or are wondering about its cost, there are a few basic things to know.
Before you buy Lotensin online, make sure you have a prescription from your doctor, as it is a prescription drug. It is also important to make sure that the pharmacy is reliable and the payment transactions on its website are secure.
The price of Lotensin can vary depending on the region, the pharmacy and the availability of promotions or discounts. Usually, the cost can range from moderate to high, but periodic promotions may allow you to purchase Lotensin cheaply.
If the original Lotensin seems expensive to you, you can consider your options for buying generic. Generic Lotensin contains the same active ingredient, benazepril, and is usually offered at a lower price. This is a good way to save money without sacrificing the quality of your treatment.
Our pharmacy offers better deals on Lotensin and other drugs at an adequate price.
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