Malival AP, 28 Caps extended release. (Malival AP) Indomethacin

Malival para que sirve?

Malival is a medicine that belongs to the group of non-steroidal anti-inflammatory drugs. The main active ingredient of the drug is Indomethacin, which helps to manage symptoms caused by various inflammatory diseases. As an analgesic, Malival AP helps reduce pain by blocking the prostaglandins that cause it. This makes it useful for relieving pain associated with inflammatory diseases such as arthritis, gout, tendon inflammation, and many other conditions. In addition to the active ingredient, the capsules also contain excipients that help form the capsule itself and improve its properties.

Composición de Malival AP

• Indomethacin: The main ingredient of the drug, aims to reduce inflammation and pain of various origins.
• Microcrystalline cellulose: Used as a filler, it provides the necessary consistency and volume of the capsule.
• Starch: Acts as a binder that helps hold the shape of the capsule.
• Magnesium stearate: Usually used to prevent the ingredients contained in the capsule from sticking together.
• Gelatin: The shell of the capsule is usually made of gelatin, providing strength and shape, and also helping to preserve the composition of the medication before it enters the stomach.

¿Para qué sirve Malival-AP?

Malival AP capsules, which contain the active ingredient indomethacin, are often used in medicine to treat a variety of conditions associated with inflammation and pain.

Rheumatoid Arthritis

This is a chronic inflammatory joint disease that causes pain and swelling and can even lead to loss of joint mobility. Malival tabletas, can help reduce inflammation and pain and improve joint function.

Dosage: For adults, the starting dose is usually 25 mg 2–3 times a day. Depending on the response to the drug and the severity of symptoms, the dose can be gradually increased. The maximum daily dose should not exceed 200 mg.

Osteoarthritis

The drug relieves the symptoms of osteoarthritis caused by this disease, such as pain and stiffness of the joints.

Dosage: In osteoarthritis, the initial dosage may also be 25 mg 2–3 times a day. Depending on the patient's condition, the dose may be increased, but the total daily amount should not exceed 200 mg.

Gout

Malival AP 50 mg may be used to treat acute attacks of gout.

Dosage: For relief of acute attacks of gout, the initial dose may be significantly higher, up to 50 mg 3 times daily. Once symptoms have subsided, the dosage should be reduced to the minimally effective level.

Bursitis and tendonitis

The drug will help relieve inflammation of the tendons and bags surrounding the joints, as well as reduce pain.

Dosage: In acute bursitis or tendonitis, the initial dose is usually 75–150 mg per day, divided into several meals. Once the condition improves, the dose can be gradually reduced.

Back pain

Many people experience back pain, which can be caused by a variety of factors, including inflammation. The indomethacin found in Malival AP can be prescribed to reduce inflammation and pain in the lower back or other parts of the back.

Dosage: Doses similar to those for arthritis may be used to treat back pain, typically 25 mg 2-3 times daily, with the possibility of adjustments based on patient response.

Menstrual pain: Sometimes Malival tablets are used for severe menstrual pain due to its anti-inflammatory and analgesic effects.

Dosage: For menstrual pain relief, the dosage may vary, but usually starts with 25 mg 2-3 times a day during the painful period.

Contraindications

Allergy to indomethacin or other NSAIDs: If you have a known allergy to indomethacin or other components of the drug.

Pregnancy and breastfeeding: Malival AP is not recommended for pregnant women, especially in the last trimesters, as it may adversely affect fetal development. In addition, indomethacin can penetrate breast milk, which is dangerous for the infant.

Gastrointestinal diseases: In patients with gastric or intestinal ulcers and those who have had bleeding or perforations in the gastrointestinal tract.

Heart disease: Patients with heart failure, high blood pressure, or after a recent myocardial infarction.

Renal and hepatic insufficiency: The drug may adversely affect renal and hepatic function, therefore its use requires caution in patients with diseases of these organs.

Side effects

Gastrointestinal problems: The most common side effects are stomach disorders such as nausea, vomiting, diarrhea, constipation, and stomachaches. In rare cases, more serious problems, such as ulcers and bleeding, can occur.

Headaches and dizziness: Indomethacin can cause headaches and feelings of dizziness, which can interfere with daily activities.

Cardiac risks: Increased blood pressure, rapid heartbeat, and, in rare cases, heart failure.

Allergic reactions: Rash, itching, swelling of the face or lips, and, in extremely rare cases, anaphylactic shock.

Mental reactions: Mood disturbances, insomnia, or even depression may occur in some people.

Interaction of Malival AP with other drugs

Nonsteroidal anti-inflammatory drugs: Drugs such as ibuprofen or naproxen may increase the risk of gastrointestinal side effects, including ulcers and bleeding. Therefore, doctors rarely recommend combining several NSAIDs at the same time.

Anticoagulants: Malival may increase their effect, which will increase the risk of bleeding.

Diuretics: Using Malival ap with edema tablets such as furosemide or hydrochlorothiazide may reduce their diuretic effect. In addition, this combination may increase the risk of kidney problems.

Lithium: The drug may increase lithium levels in the blood, leading to an increase in its toxic effects.

Methotrexates: Taking Malival together with methotrexate may increase the toxicity of the latter, especially to the kidneys. This requires special caution and monitoring of the patient's condition.

Antihypertensive drugs: Malival tablets, may reduce the effectiveness of medications to control high blood pressure such as beta-blockers, ACE inhibitors and angiotensin antagonists.

So, we have found that Malival AP, is a potent anti-inflammatory drug that can effectively manage the symptoms of many inflammatory diseases. However, due to the possibility of serious side effects, it should be used under strict medical supervision and only when prescribed by a doctor.