Prednisone 5 mg is a synthetic glucocorticoid drug; a dehydrated hydrocortisone analog. It has anti-inflammatory, anti-allergic, desensitizing, anti-shock, antitoxic and immunosuppressive effects.
Prednisone is prescribed for the following conditions:
In transplantology - suppression of reaction after organ transplantation
Prednisone tablets are effective, proven and affordable medication that is still relevant today. Prednisone 5 mg is available in a pack of 40 tablets.
Prednisone 5 mg tablet stays in the body for 17 to 22 hours. The elimination half-life is on average 3 to 4 hours. It usually takes about five half-lives for the drug to be completely eliminated from the body.
Prednisone is prescribed in complex therapy when it is necessary to relieve swelling of the sinuses, since swelling is the main cause of nasal congestion. Steroids such as Prednisone and Cortisone help reduce inflammation and swelling.
Prednisone tablets stimulate appetite and can lead to weight gain, so patients are advised to follow a diet when taking the drug.
Weight gain is a common side effect of Prednisone. The drug can cause redistribution of fat on the face, back of the neck, and abdomen. The higher the dose and prolonged the treatment, the more changes.
The main difference between Prednisone and Prednisolone is that Prednisone is a prodrug that is converted by liver enzymes before it begins to show its therapeutic effects.
For people with severe liver disease, Prednisolone is preferred.
Both drugs belong to the group of glucocorticoids and are used to treat similar conditions. They are usually considered equally effective and are used to treat:
Drugs have similar side effects: acne; stomach disorders; an increase in body weight; sleep disturbances; fluid retention; facial hair growth; mood changes; high blood pressure; loss of bone mass; osteoporosis.
Both drugs may inhibit growth and development in children. Dosing schedules for Prednisone and Prednisolone are usually similar, ranging from 5 mg to 60 mg per day.
Prednisone is prescribed for coughs. The mechanism of the antishock effect of Prednisone is associated with a decrease in the synthesis of platelet-activating factor (mediator of shock), as well as a decrease in extraneuronal uptake and an increase in the pressor effect of catecholamines.
Prednisone is one of the most common corticosteroids used to treat bronchitis, especially if you have asthma or chronic obstructive pulmonary disease (COPD).
Taking Prednisone and alcohol develops gastric erosion and ulcers, which are often complicated by bleeding. From such a double burden of harmful substances, the liver suffers.
Hormones also act on the CNS. Various mental disorders manifest this. Therefore, the compatibility of Prednisone with alcohol is impossible, because the existing disorders will be added to the toxic effects of ethanol on the brain.
Metabolism of hormonal drugs mainly takes place in the liver. Alcohol can greatly accelerate these processes and reduce the half-life of the medication. This affects the concentration of the hormone in the blood and its therapeutic effect.
If you forgot to take Prednisone and took a sufficient dose of alcohol, it is worth immediately rinsing the stomach (drink a lot of warm water and provoke a gag reflex). If there are signs of poisoning or intoxication – call an ambulance immediately!
Prednisone is prescribed for hyperuricemia, which has a pronounced analgesic, anti-inflammatory and anti-edema effect. The drug is not recommended for a long time and is prescribed only in extreme cases, if the attack is very severe, and NSAIDs are ineffective enough to relieve the pain syndrome. Approximately all corticosteroids have a similar mechanism of action. For rheumatoid exacerbation and joint pain, the doctor may also prescribe Prednisone. The duration of therapy with pills should not exceed 2 weeks, as there is an increased risk of hormonal disruption, increased blood sugar levels and arterial hypertension.
Glucocorticosteroids, such as Prednisone, are often prescribed to reduce chronic back pain when conventional conservative treatments such as rest, exercise and over-the-counter medications do not have the desired effect. Corticosteroids help soothe pain and reduce swelling at the site of inflammation.
Patients receiving Prednisone, like other GCSs, may develop arterial hypertension in high doses. Tell your doctor if any side effect occurs, and the specialist will prescribe a lower dose or replace it with another drug.
The dose and duration of treatment are selected by the doctor individually, depending on the indications and the severity of the disease.
Usually, the daily dose is taken once or take a double dose every other day, in the morning hours, between 6 and 8 a.m. The drug is recommended to be taken in the morning to reduce the risk of insomnia in the evening.
The high daily dose can be divided into 2-4 doses, with a higher dose to be taken in the morning. The tablets should be taken during or immediately after a meal, with a small amount of liquid.
In acute conditions and as substitution therapy in adults, an initial dose of 20-30 mg/day is prescribed, and the maintenance dose is 5-10 mg/day. In some diseases (nephrotic syndrome, some rheumatic diseases) higher doses are prescribed. Treatment is stopped slowly, gradually reducing the dose. If a patient has a history of psychosis, high doses are prescribed under close medical supervision.
Doses for children: initial dose is 1-2 mg/kg/day in 4-6 doses, maintenance dose is 0.3-0.6 mg/kg/day.
When prescribing, the daily secretory rhythm of glucocorticosteroids should be taken into account: most (or all) of the dose of the drug is prescribed in the morning.
We offer a reasonable price for customers of our online pharmacy. You will be able to buy Prednisolone without a prescription, the price includes a prescription from a specialist.
At any time convenient for you, you can go to the website and find out what is the price of the drug you are interested in.
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