Stromectol Ivexterm Ivermectin 6 mg 4 tabs

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What is Ivermectin?

Ivermectin is a drug that is effective against many nematodes (roundworms). Therefore, the active ingredient is used orally or topically for the following indications:

  1. Gastrointestinal strongyloidiasis (anguillulosis, pygmy ascaridae)
  2. Suspected or diagnosed microfilaremia in patients with lymphatic filariasis
  3. Scabies (pruritus) caused by Sarcoptes scabei in people with a clear clinical or parasitological diagnosis
  4. Topical treatment of inflammatory lesions (papulopustular) rosacea
  5. The drug's active ingredient is FDA approved for the treatment of onchocerciasis (river blindness). Ivermectin tablets are also used to treat COVID-19.

Pharmacokinetics of the drug

The pharmacokinetics of the drug consists of sequential steps: absorption, distribution, metabolism, and excretion.

Absorption. Ivermectin is absorbed to a small extent after topical application. Absorption of Ivermectin pills is significantly higher, with maximum plasma levels reached after approximately four hours.

Distribution. More than 99% of the active substance is bound to plasma proteins, mainly serum albumin. Ivermectin passes poorly through the blood-brain barrier.

Metabolism. The drug is metabolized by the CYP3A4 enzyme. 

Excretion. The drug is excreted in the feces and less than 1% via the kidneys. Half-life after a single dose is 12 hours, while metabolites have a half-life of about three days. With regular topical administration, the half-life increases to six days.

How to take Ivermectin?

Ivermectin is taken orally as a tablet or applied to the skin as a hydrophilic cream.

Oral administration of Ivermectin is recommended on an empty stomach. Tablets are washed down with water. For children under six years of age, they can be crushed beforehand. The dosage depends on body weight and indications.

How to take Ivermectin for humans for COVID-19?

The drug began to be used in pharmacology 40 years ago. The active ingredient is effective against various parasites, which contributed to the eradication of the “pandemic” of parasitic diseases on several continents.

Studies in recent years have shown that the drug has anti-inflammatory and antiviral effects. In many countries, Ivermectin 6 mg tablet is used to treat COVID-19.

It should be noted that the highest effectiveness of the drug is shown in the treatment protocol, which also includes other drugs and supplements approved by the FDA.

Where to buy Ivermectin?

Over-the-counter Ivermectin can be ordered from a Mexican pharmacy. Before purchasing the medicine, it is recommended to consult a doctor about taking the medication.

At the consultation, the doctor will determine the dosage and duration of treatment in the case of your disease. You can also buy Ivermectin together with other medicines prescribed by your doctor for an effective treatment.

Ivermectin: Dosage

Oral administration of Ivermectin is recommended for people weighing more than 15 kg, because the blood-brain barrier has not yet fully formed. The dosage of the drug depends on the type and degree of the disease. One tablet usually contains 3 mg of the active substance.

Dosage of the drug in various diseases

Gastrointestinal strongyloidiasis: the recommended dose of ivermectin is 200 mcg per kg body weight.

Microfilaremia caused by Wuchereria bancrofti: Mass treatment of microfilaremia caused by Wuchereria bancrofti is prescribed as a single oral dose every six months.

The recommended dose is 150 to 200 mcg of the drug per kilogram of body weight.

In endemic areas, the drug may be administered only once every 12 months, with a recommended dose of 300 to 400 mcg/kg. Alternatively, the dosage can also be determined according to body weight.

Scabies (itching). For the treatment of scabies, a single drug dose of 200 mcg per kilogram of body weight is recommended. In the case of common scabies, healing can only be determined with certainty after about four weeks.

If new specific lesions appear or if parasitological tests are positive, a second dose may be required in exceptional cases after two weeks. If you already have experience with ivermectin, you can buy ivermectin online from our pharmacy with delivery to your state. 

Ivermectin: Dosage for COVID-19

The drug for viral diseases is used in a dosage of 150-200 mcg per 1 kg of human weight. This dosage is the safest, in which the drug is most effective and does not harm human health.

Avermectin vs Ivermectin

Ivermectin and Avermectin are drugs of the same group, which act by interacting with chloride channels in the membranes of nerve and muscle cells. This leads to hyperpolarization of the affected cells and subsequent paralysis and death of parasites.

It should also be noted that Ivermectin belongs to the avermectin group, which has an anti-inflammatory effect by inhibiting the production of inflammatory cytokines induced by lipopolysaccharides.

Ivermectin: interactions

No clinical studies have been carried out on the drug's interaction with other substances.

At the same time, the active substance of the drug is metabolized with the help of CYP3A4 enzyme, so care should be taken when using CYP3A4 inhibitors with the drug Ivermectin.

Ivermectin: side effects

Side effects of taking Ivermectin tablets depend on the density of microfilariae in the blood. Hypersensitivity reactions may occur in some patients when taking the drug.

The following additional side effects have been observed with oral therapy:

  • Transient hypereosinophilia
  • Liver dysfunction
  • Gastrointestinal problems (diarrhea, vomiting, nausea)
  • Weakness, fatigue, dizziness
  • Severe skin reactions (such as Stevens-Johnson syndrome) are very rare

Where to buy Ivermectin?

Buy Ivermectin online from a Mexican online pharmacy. Your doctor will help you decide the dosage and indications for use. Follow your doctor's recommendations when taking Ivermectin pills.

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