Augmentin Jr Susp 12H 60 ml (Amoxicilina/Acido Clavulanico)

Augmentin is a well-known antibiotic used to treat various bacterial infections in children. This drug combines amoxicillin, which belongs to the penicillin group, and clavulanic acid, which prevents bacterial enzymes from breaking down amoxicillin, thereby enhancing its antibacterial effect. These infections include otitis media, sinusitis, respiratory infections, urinary tract infections, and skin infections.

Augmentin liquid (suspension) is especially convenient for children, as it is easier to take and dose.

The use of Augmentin should be strictly in accordance with the doctor's recommendations, including the duration of the course of treatment, even if the symptoms of infection disappeared early.

The mechanism of action is that amoxicillin disrupts the synthesis of the cell wall of bacteria, as a result of which they die. Clavulanic acid, in turn, blocks bacterial enzymes that can break down amoxicillin, thus ensuring its effectiveness against a wide range of bacteria.

Side effects and contraindications

Despite its high efficacy, like any medical remedy, Augmentin has a number of contraindications and potential side effects that are important to familiarize yourself with before starting treatment.

Contraindications to the use of Augmentin:

• Allergy: Having an allergy to amoxicillin, clavulanic acid, or any other penicillins is an absolute contraindication. Symptoms of allergy may include rash, itching, swelling, difficulty breathing, and anaphylaxis.
• History of hepatic disease: Patients with a history of hepatic disorders, especially those caused by previous antibiotic use, should avoid taking Augmentin because of the risk of liver deterioration.
• Gilbert's Phenomenon: People with this condition should be cautious when using Augmentin as it may lead to increased levels of bilirubin in the blood.
• Mononucleosis and lympholeukemia: Patients with infectious mononucleosis or lympholeukemia may face an increased risk of developing skin rashes while taking Augmentin.

Side effects of Augmentin use:

• Gastrointestinal Disorders: The most common side effects associated with taking Augmentin include nausea, vomiting, diarrhea, and abdominal pain. In some cases, antibiotic-associated colitis may develop.
• Skin reactions: Like other antibiotics, Augmentin can cause a variety of skin reactions, ranging from mild rashes to serious conditions such as erythema multiforme and Stevens-Johnson syndrome.
• Pseudomembranous colitis: This is a serious bowel disease that can develop as a result of antibiotic therapy, including Augmentin treatment. Symptoms include severe diarrhea, abdominal pain, and fever.
• Liver disorders: In rare cases, Augmentin may cause an increase in liver enzymes, jaundice, and, in very rare cases, acute hepatitis.
• Increased bilirubin and creatinine levels: In some cases, Augmentin may cause increased bilirubin and creatinine levels in the blood, which requires careful monitoring in patients with kidney disease.
• Allergic Reactions: In addition to local allergic reactions such as rash and itching, Augmentin may cause more serious systemic reactions, including angioedema (Quincke's edema), anaphylaxis, and serum sickness.
• Effect on blood: In rare cases, taking Augmentin may cause leukopenia, thrombocytopenia, anemia and other blood changes that require immediate attention.
• Headache and dizziness: Some patients may experience headaches and dizziness during Augmentin treatment.
• Candidiasis: Prolonged use of Augmentin may contribute to the development of candidiasis (a fungal infection) because the antibiotic can disrupt the normal balance of microflora in the body.
• Hypersensitivity reactions: In rare cases, hypersensitivity reactions such as vasculitis and interstitial nephritis may occur.

Dosage

Adults and children over 12 years of age:

Mild to moderate infections (e.g., respiratory tract infections):

The standard dose is 500 mg amoxicillin/125 mg clavulanic acid every 8 hours or 875 mg amoxicillin/125 mg clavulanic acid every 12 hours.

More severe infections, including chronic sinusitis, pneumonia, and skin and urinary tract infections:

A dose increase to 875 mg amoxicillin/125 mg clavulanic acid every 8 hours may be required.

Children under 12 years of age:

The dosage for children is usually calculated based on the child's weight and the type of infection. Augmentin is often prescribed in oral suspension form for children.

The usual dose for children is about 25 mg of amoxicillin per kilogram of the child's weight, divided into two doses throughout the day.

For more serious infections, the dose may be increased to 45 mg of amoxicillin per kilogram of the child's weight, divided into two doses during the day.

Special Cases:

Patients with impaired renal function may require dose adjustments or increased intervals between doses, depending on the degree of renal impairment.

In cases of acute otitis media in children, a high dose may be recommended to maximize efficacy against the infectious agent.

Administration and duration of treatment

Augmentin is usually taken at the beginning of a meal to minimize gastrointestinal side effects.

The duration of the course of treatment is usually 7 to 14 days, depending on the doctor's recommendations and the severity of the infection. It is important to complete the entire course, even if symptoms disappear early, to prevent the risk of developing antibiotic resistance.

Augmentin 12 h indicates a form of the drug with prolonged action, which is usually taken every 12 hours to ensure a stable concentration of the drug in the blood.

Augmentin online

Augmentin is available in Australia under the same International Nonproprietary Name (INN), Augmentin, which is used in many countries around the world. The drug is manufactured by GlaxoSmithKline (GSK), which is one of the largest pharmaceutical manufacturers in the world. In the Australian market, Augmentin is available in various forms, including tablets, liquid oral suspension (particularly popular for pediatric use), and powder for preparing injections.

Augmentin holds a significant place in the pharmaceutical market in Mexico. In this country, the drug is available both in its original form and as a variety of generics that offer a more affordable alternative while maintaining therapeutic efficacy.

Augmentin generics are alternative versions of the drug that contain the same active ingredients (amoxicillin and clavulanic acid) and are intended to treat the same conditions. In Mexico, these generics are produced by many pharmaceutical companies, which helps increase the availability of the drug to the general population.

You can purchase Augmentin or its generics in Mexico either at traditional pharmacies or through online pharmacies. Online shopping offers convenience and privacy, allowing patients to get the medication they need without having to leave their homes. Many online pharmacies in Mexico offer a wide range of generic Augmentin, allowing customers to choose a product according to their preferences and financial capabilities.

The cost of Augmentin and its generics in Mexico can vary depending on a variety of factors, including the manufacturer, dosage form (tablets, suspension, etc.), dosage, and place of purchase. In general, generics are usually offered at a lower price than the original drug, making them an attractive option for many patients. Online pharmacies can also offer competitive prices and special offers, making the purchase even more affordable.

Interaction

Augmentin, a combination of amoxicillin and clavulanic acid, is an effective antibiotic widely used to treat a variety of bacterial infections. However, like many other medicines, Augmentin may interact with other medicines, which may affect their effectiveness or increase the risk of side effects. It is important to inform your doctor of all medications you are taking, including over-the-counter medications, vitamin supplements, and herbal remedies, before starting Augmentin treatment. Below are some known interactions of Augmentin with other medications.

Anticoagulants

Augmentin may increase the effects of anticoagulants such as warfarin, increasing the risk of bleeding. If you are taking anticoagulants, your doctor may recommend more frequent blood monitoring to monitor the effects of the anticoagulant.

Allopurinol

Combining Augmentin and allopurinol may increase the risk of skin allergic reactions such as hives and rashes. If these drugs are used at the same time, possible skin reactions should be carefully monitored.

Methotrexate

Augmentin may increase the toxicity of methotrexate, a drug used to treat some cancers and rheumatoid arthritis, by increasing the risk of its side effects.

Oral contraceptives

Although the issue is still a matter of scientific debate, it is believed that antibiotics, including Augmentin, may reduce the effectiveness of oral contraceptives. This may increase the risk of an unwanted pregnancy. As a precautionary measure, some doctors recommend using additional methods of contraception during antibiotic treatment.

Probenecid

Probenecid, used to treat gout, may increase the concentration of amoxicillin in the blood, delaying its excretion by the kidneys. This may result in an increase or prolongation of the effects of amoxicillin, necessitating a dose adjustment.

Other antibiotics

Combining Augmentin with other antibiotics, especially bacteriostatic antibiotics (e.g., tetracyclines and macrolides), may result in a mutual decrease in their effectiveness due to differences in mechanisms of action.

Drugs to reduce stomach acidity

The use of drugs to reduce stomach acidity, such as antacids containing magnesium or aluminum, and drugs that reduce the production of gastric juice (such as proton pump inhibitors or H2-blockers), may affect the absorption of amoxicillin. This may slightly reduce the effectiveness of Augmentin. It is recommended that an interval of 2–3 hours be observed between the administration of these drugs and Augmentin.

Live oral typhoid vaccines

Antibiotics, including Augmentin, may interact with live oral typhoid vaccines, reducing their effectiveness. If vaccination is planned, your doctor should be notified.

Diuretics

Although there is little direct evidence of interaction between Augmentin and diuretics (diuretics), there is a theoretical risk that the antibiotic may increase the risk of side effects of some diuretics, especially with respect to kidney function.

Myoflaxin and other nonsteroidal anti-inflammatory drugs (NSAIDs)

Some studies suggest that myoflaxin and other NSAIDs may increase blood concentrations of amoxicillin, potentially increasing both the effectiveness and risk of side effects of the antibiotic.

Alcohol

Although there is no direct interaction between alcohol and Augmentin, alcohol consumption during antibiotic treatment may increase the negative effects on the liver and worsen the overall condition of the body, slowing down the healing process.

Medications to treat hyperuricemia

Medications such as allopurinol and other drugs used to control uric acid levels in the blood may interact with Augmentin, increasing the risk of skin reactions.

Overall, Augmentin Jr Susp 12H is an effective treatment for bacterial infections in children, but its use should be strictly regulated by medical guidelines and under the supervision of a physician, especially considering the possibility of side effects and the risk of antibiotic resistance.