Avelox, 5 tabs. (Avelox) moxifloxacin

Avelox (moxifloxacin) is an antibiotic from the group of fluoroquinolones used to treat various types of bacterial infections. The drug is produced in the form of tablets, and the most common dosage is 400 mg. Avelox is effective in treating respiratory tract infections, skin infections, as well as intra-abdominal infections and many other conditions.

What is Avelox?

Moxifloxacin, the active ingredient in Avelox, blocks DNA gyrase and topoisomerase IV, enzymes that bacteria need to copy and repair their DNA, resulting in the death of the bacteria. This mechanism of action makes What is Avelox a powerful tool in the fight against infections.

Avelox uses

Avelox 400 is a powerful antibiotic from the group of fluoroquinolones for the treatment of a wide range of bacterial infections. It is used in the form of tablets or injections and is particularly effective in treating respiratory tract infections, skin infections, as well as abdominal and sexually transmitted infections.

Indications for Avelox treatment

• Acute bacterial sinusitis: Avelox reduces inflammation and kills the bacteria causing sinus infection.
• Chronic bronchitis exacerbation: The drug helps to kill the bacteria causing the exacerbation of symptoms.
• Community-acquired pneumonia: Antibiotic Avelox is widely used to treat pneumonia caused by bacterial infection, regardless of the severity of the disease.
• Skin infections: Effective in treating infections of the skin and skin structures, including infections resistant to other antibiotics.

Main Avelox dosage recommendations

• Acute bacterial sinusitis and chronic bronchitis in the stage of exacerbation: The standard dose of Avelox is 400 mg once a day. The course of treatment usually lasts from 5 to 10 days.
• Pneumonia acquired outside the hospital: The dose is also 400 mg once daily, but the course of treatment may be increased to 7 to 14 days depending on the severity of the disease and the patient's clinical response.
• Uncomplicated cutaneous and structural skin infections: Take Avelox 400 mg tablets once daily for 7–14 days. For more serious infections, the dosage may be adjusted by the treating physician.
• Complicated intra-abdominal infections: The recommended dose is Avelox 400mg tabs once daily for 5-14 days, depending on the type and severity of the infection.
• Uncomplicated urethritis or cervicitis caused by Neisseria gonorrhoeae: A single dose of 400mg.
• Mycoplasma and Chlamydia infections: May require a longer course of treatment, usually 400 mg daily for 10–14 days.

Contraindications to the use of Avelox

• Allergic reactions: Avelox medicine should not be taken by people with known hypersensitivity to moxifloxacin or other drugs in the fluoroquinolone group, as serious allergic reactions may result.
• Age restrictions: Avelox antibiotic is generally not recommended for patients under 18 years of age due to the potential risk of joint and cartilage damage.
• Pregnancy and lactation: The drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Moxifloxacin is excreted with breast milk, so it is not recommended during breastfeeding.
• Heart disease: Avelox may increase the risk of serious arrhythmias, so it should be avoided in patients with known heart rhythm disorders or other serious heart disease.

Medication Avelox side effects

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Gastrointestinal disorders
• Tendonitis and tendon rupture, especially in the elderly
• Heart problems, including QT interval prolongation and the risk of tachycardia
• Liver damage, up to fulminant hepatitis
• Neurological disorders, including peripheral neuropathy and possible psychotic reactions
• Photosensitivity results in severe light burns
• Serious allergic reactions, including anaphylaxis and toxic epidermal necrolysis
• Lowering of glucose levels, which can be dangerous for diabetics
• Psychological effects such as depression or hallucinations

Avelox drug interaction

Antacids and preparations containing iron, zinc, magnesium or aluminum: These substances may slow down or reduce the absorption of moxifloxacin, which reduces its effectiveness. It is recommended that you take Avelox at least 4 hours before or 8 hours after these drugs.

Drugs to reduce gastric acidity (e.g., proton pump inhibitors and H2-histamine blockers): Such medications may also affect the absorption of moxifloxacin, so they should be taken in consideration of the indicated time interval.

Drugs affecting the heart rhythm (e.g. antiarrhythmic drugs): Moxifloxacin may increase the risk of cardiac arrhythmias, especially QT interval prolongation, so its combination with other drugs that affect the QT interval requires caution.

Immune-suppressing drugs: Patients taking immunosuppressants may be more susceptible to infections and side effects, which requires additional monitoring when using Avelox.

Nonsteroidal anti-inflammatory drugs (NSAIDs): The combination of NSAIDs and moxifloxacin may increase the risk of neurologic side effects such as seizures.

Oral hypoglycemic agents and insulin: Avelox medication may affect blood glucose levels, which requires dosage adjustment of these drugs in diabetic patients.

Warfarin and other anticoagulants: Moxifloxacin may enhance the effects of warfarin and increase the risk of bleeding, which requires careful monitoring of blood coagulation parameters.

Cost and availability of Avelox

The main form of release, Avelox 400 mg tablets, is widely used in clinical practice. The 400 mg tablets are easy to use and are usually prescribed for a treatment course of 5 to 14 days, depending on the diagnosis.

The cost of Avelox 400 mg may vary by region, pharmacy, and insurance coverage. Patients may need to do a little research to compare prices across different pharmacies or online platforms. Avelox price may be higher in places where the drug is less available or if it is not on the list of medications covered by insurance.

Despite the high Avelox cost, it is widely available at most pharmacies. However, in some cases, alternatives may be considered in the form of Avelox generic, which may offer comparable efficacy at a lower price, making it an affordable choice for patients on a tight budget. Patients should discuss the possibility of replacing moxifloxacin with a generic with their physician to ensure its acceptability and effectiveness for their particular case.

Avelox reviews

Most patients taking Avelox 400mg tablets report that the drug is highly effective in treating infections. However, some experience side effects that may affect their quality of life. It is important to weigh the potential benefits and risks before starting treatment and discuss them with your doctor.

Overall, when prescribed correctly and following all precautions, Avelox remains an important tool in the treatment of serious bacterial infections. Always follow your doctor's instructions and do not stop taking the antibiotic without consulting a medical professional, even if the symptoms of the infection have disappeared.