Galvus Met Vildagliptin Metformin 50mg / 500mg 30 Tabs

Galvus Met is a combination medication used for the treatment of type 2 diabetes mellitus. It contains two active substances: Vildagliptin 50mg and Metformin 500mg, which work together to better control blood sugar levels in patients suffering from this disease. This drug is prescribed when diet and physical activity fail to provide sufficient glycemic control.
 

Mechanism of action
 

Galvus has a highly effective action due to the synergistic work of its two active components, increasing insulin production and reducing glucagon levels (a hormone that stimulates glucose production in the liver), as well as blocking excessive glucose production in the liver and improving its absorption by cells, thus reducing blood sugar levels. Let's take a look at exactly how the components of the medicine Galvus work.

Vildagliptin is an inhibitor of the enzyme dipeptidyl peptidase-4, it increases glucose-induced insulin secretion and decreases glucagon release. This helps normalize blood sugar levels both on an empty stomach and after meals. Vildagliptin helps increase the concentration of incretins, the hormones that stimulate insulin production in response to food intake. It also improves the function of pancreatic beta cells, which are responsible for insulin production.

Metformin reduces glucose production in the liver, increases tissue sensitivity to insulin, and slows glucose absorption in the intestine. Its action results in lower blood sugar levels, especially on an empty stomach. Metformin also helps to reduce the risk of cardiovascular disease in patients with diabetes.
 

Indications for use
 

Galvus medicine is prescribed for the treatment of patients with type 2 diabetes mellitus, when monotherapy with metformin or another sugar-lowering drug does not give sufficient results. The drug is used as:

• Monotherapy (Galvus Met alone) in patients in whom diet and exercise do not provide sugar control.
• In combination with other sugar-lowering drugs such as insulin or sulfonylurea derivatives.
   

Method of administration and dosage
 

Galvus 50 mg, is taken orally, preferably with meals, to minimize the risk of gastrointestinal side effects, especially those associated with metformin. The dosage is selected individually, depending on the current sugar level and the patient's response to treatment.

• The initial dosage of the drug depends on the dosage of the components that the patient was taking before. Usually, start with one tablet of Galvus Met 50/500 twice a day.
• The maximum daily dose of vildagliptin is 100 mg, which corresponds to two tablets per day.
• Metformin can be increased up to 2000 mg per day, depending on the individual reaction of the patient and the tolerability of the drug. In such cases, the drug with a dosage of Galvus Met 50/1000 is used

It is important to follow the doctor's dosage recommendations, as incorrect use can lead to the development of side effects.
 

Contraindications
 

• Renal function disorders or renal failure (creatinine clearance less than 60 ml/min).
• Liver disease, as metformin may cause lactoacidosis, a serious and potentially fatal complication.
• Acute conditions accompanied by the development of hypoxia, such as respiratory failure, heart failure or myocardial infarction.
• Alcoholism, acute alcohol intoxication.
• Pregnancy and lactation period, since the safety of vildagliptin and metformin use in these periods has not been established.
• The drug is also contraindicated in children under 18 years of age.
   

Side effects
 

• Gastrointestinal tract: nausea, vomiting, diarrhea, abdominal pain, bloating, and flatulence. These symptoms are often associated with metformin, especially at the beginning of treatment, but they may decrease with time.
• Skin: rash, itching, urticaria.
• Nervous system: headache, dizziness, tremor.
• Muscle pain may occur with prolonged use of vildagliptin.
• Lactoacidosis: a rare but dangerous complication associated with metformin. Symptoms include deep breathing, weakness, abdominal pain, and a decreased body temperature. Lactoacidosis requires immediate medical attention.
   

Interactions with other medications
 

When using Galvus 50, it is important to consider interactions with other medications:

• Drugs that affect kidney function, such as nonsteroidal anti-inflammatory drugs (NSAIDs), may increase the risk of metformin side effects, including lactoacidosis.
• Angiotensin-converting enzyme (ACE) inhibitors, such as captopril and enalapril, may increase the sugar-lowering effects of metformin.
• Drugs that increase blood glucose levels (corticosteroids, thiazide diuretics) may weaken the effect of Galvus metformin.
   

Special instructions
 

1. Renal function monitoring: before starting treatment, it is necessary to assess the patient's renal status and regularly monitor their function during treatment.
2. Alcohol intake: alcohol intake during therapy should be avoided, as it may increase the risk of lactoacidosis.
3. Pregnancy and lactation: the drug is contraindicated, so in cases of planned pregnancy or at its onset, it is necessary to stop taking it.
    

Galvus Met online
 

Purchase of the medication Galvus is possible, both in conventional and online pharmacies, which provides patients with a choice of a convenient method of purchase. The Galvus met 50/500 price varies depending on the dosage and region, but for those looking for an economical option, online pharmacies can offer more favorable purchase terms.

In most countries, Galvus metformin is not an over-the-counter drug, as its ingredients require monitoring by a physician, especially in patients with impaired kidney or liver function.

Nevertheless, in Mexican online pharmacies, there are offers to sell Galvus otc, but it is necessary to choose only trusted pharmacies where you will be sure of purchasing quality medication.

Galvus Met is a fairly effective medicine for the treatment of type 2 diabetes mellitus, combining a combination of two powerful components that, through their action, help to improve blood sugar control by stimulating insulin production and reducing glucose production in the liver. It is suitable both for monotherapy and for complex treatment with other sugar-lowering agents, which makes it flexible in its use. The use of Galvus medicine will significantly improve the quality of life of people with type 2 diabetes and help to effectively manage the disease, minimizing the risks of complications.